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AI identifies potent inducers of breast cancer stem cell differentiation based on adversarial learning from gene expression data

27 Mar 2024

Abstract excerpt

Cancer stem cells (CSCs) are a subpopulation of cancer cells within tumors that exhibit stem-like properties and represent a potentially effective therapeutic target toward long-term remission by means of differentiation induction. By leveraging an artificial intelligence approach solely based on transcriptomics data, this study scored a large library of small molecules based on their predicted ability to induce...

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PMID: 38701411
DOI: 10.1093/bib/bbae207

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