Article
No genetic causal association between periodontitis and ankylosing spondylitis: a bidirectional two-sample mendelian randomization analysis.
BMC medical genomics - 2 May 2024
Han Chong, Wu Dongchao, Yu Feiyan, Wang Qianqian, Yang Yang, Li Yi, Qin Rao, Chen Yue, Xu Linkun, He Dongning
Abstract excerpt
BACKGROUND: Observational studies that reveal an association between periodontitis (PD) and ankylosing spondylitis (AS) exist. However, observational research is prone to reverse causality and confounding factors, which make it challenging to infer cause-and-effect relationships. We conducted a two-sample Mendelian randomization (MR) study to examine the causal relationship between the genetic prediction of PD...
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