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Article

Causal Association between Periodontitis and Parkinson's Disease: A Bidirectional Mendelian Randomization Study.

Genes - 19 May 2021

Botelho João, Machado Vanessa, Mendes José João, Mascarenhas Paulo

Abstract excerpt

The latest evidence revealed a possible association between periodontitis and Parkinson's disease (PD). We explored the causal relationship of this bidirectional association through two-sample Mendelian randomization (MR) in European ancestry populations. To this end, we used openly accessible data of genome-wide association studies (GWAS) on periodontitis and PD. As instrumental variables for periodontitis,...

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Identifiers

PMID: 34069479
DOI: 10.3390/genes12050772
PMCID: PMC8159074

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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