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Article

Evaluation of bi-directional causal association between periodontal disease and erectile dysfunction: a two-sample Mendelian randomization study.

Clinical oral investigations - 1 Oct 2023

Yu Feiyan, Wang He, Wang Qianqian, Zhao Baoling, Zhao Zhenni, Bian Wei

Abstract excerpt

BACKGROUND: The association between periodontal disease (PD) and erectile dysfunction (ED) has been well-documented in observational studies. However, observational studies are vulnerable to reverse causality and confounding factors, making the inference of causal-effect relationships challenging. Contrary to the current belief, Mendelian randomization (MR) can be applied to comprehensively assess the...

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PMID: 37581767
DOI: 10.1007/s00784-023-05201-0

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