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Engineering Cell Instructive Microenvironments for In Vitro Replication of Functional Barrier Organs

2 May 2024

Abstract excerpt

Multicellular organisms exhibit synergistic effects among their components, giving rise to emergent properties crucial for their genesis and overall functionality and survival. Morphogenesis involves and relies upon intricate and biunivocal interactions among cells and their environment, that is, the extracellular matrix (ECM). Cells secrete their own ECM, which in turn, regulates their morphogenetic program by...

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PMID: 38695274
DOI: 10.1002/adhm.202400357

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