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Article

"Quadruple-hit" primary testicular diffuse large B-cell lymphoma with MYD88 L265P mutation, IGH::MYC, and IRF4- and BCL6-rearrangements.

Journal of hematopathology - 1 Sept 2023

Bruehl Frido K, Ketterling Rhett P, Rimsza Lisa M, Santos Edward F, McPhail Ellen D

Abstract excerpt

Classification of DLBCL relies on clinical, immunohistochemical, and genetic information. We report a case of primary testicular diffuse large B-cell lymphoma (PT-DLBCL) with a hitherto unreported constellation of pathologic findings to illustrate the challenges of DLBCL classification. A standard hematopathology workup was followed by gene expression profiling (GEP) to determine the DLBCL cell of origin (COO). A...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38175404
DOI: 10.1007/s12308-023-00556-5

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