Article
A cold case of hemolytic disease of the fetus and newborn resolved by genomic sequencing and population studies to define a new antigen in the Rh system.
Transfusion - 1 Jun 2024
Wilson Brett, Davison Candice L, Lopez Genghis H, Millard Glenda M, Liew Yew-Wah, Powley Tanya, Campbell Tamika, Jadhao Sudhir S, Nagaraj Shivashankar H, Perry Maree, Roulis Eileen V, Toombs Maree, Irving David O, Flower Robert L, Hyland Catherine A
Abstract excerpt
BACKGROUND: We report an obstetric case involving an RhD-positive woman who had developed a red blood cell (RBC) antibody that was not detected until after delivery of a newborn, who presented with a positive direct antiglobulin test result. Immunohematology studies suggested that the maternal antibody was directed against a low-prevalence antigen on the paternal and newborn RBCs. RESULTS: Comprehensive blood...
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