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Article

Identification of a novel MYO1D variant associated with laterality defects, congenital heart diseases, and sperm defects in humans.

Frontiers of medicine - 1 Jun 2024

Yuan Zhuangzhuang, Zhu Xin, Xie Xiaohui, Wang Chenyu, Gu Heng, Yang Junlin, Fan Liangliang, Xiang Rong, Yang Yifeng, Tan Zhiping

Abstract excerpt

The establishment of left-right asymmetry is a fundamental process in animal development. Interference with this process leads to a range of disorders collectively known as laterality defects, which manifest as abnormal arrangements of visceral organs. Among patients with laterality defects, congenital heart diseases (CHD) are prevalent. Through multiple model organisms, extant research has established that...

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PMID: 38684630
DOI: 10.1007/s11684-023-1042-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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