Investigation of Genetic Association Between a High Activity Variant of Cathepsin G and Risk for Basal Cell Carcinoma.

doi:10.21873/anticanres.17013

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Investigation of Genetic Association Between a High Activity Variant of Cathepsin G and Risk for Basal Cell Carcinoma.

Anticancer research - 1 May 2024

Douka Anna, Gintoni Iphigenia, Derka Spyridoula, Vairaktari Georgia, Vassiliou Stavros, Yapijakis Christos

Abstract excerpt

BACKGROUND/AIM: Cathepsin G (CTSG) has been identified as an inhibitor of breast, bladder, and colorectal cancers. The G allele of the N125S (A/G, rs45567233) functional polymorphism of the CTSG gene confers increased serum CTSG activity and has been associated with cardiovascular and neurovascular diseases. This study examined the possible correlation between the pathogenesis of basal cell carcinoma (BCC) and...

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PMID: 38677729
DOI: 10.21873/anticanres.17013

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