Article
Mother's smoking habits affects IL10 methylation but not asthma in Ecuadorian children.
Molecular genetics & genomic medicine - 1 Apr 2024
Ochoa-Avilés Cristina, Ochoa-Avilés Angélica, Rivas-Párraga Roque, Escandón Samuel, Santos-Jesus Talita Dos, Silva Milca de J, Leão Valderiene, Salinas Marco, Vicuña Yosselin, Baldeón Lucy, Molina-Cando María José, Morillo Diana, Machuca Marcos, Rodas Claudia, Figueiredo Camila, Neira Vivian Alejandra
Abstract excerpt
There is no evidence evaluating the IL10 epigenetic upregulation among mestizo children in a high-altitude Andean city in Latin America. OBJECTIVE: To identify polymorphisms and methylation profiles in the IL10 gene associated with asthma in children aged 5 to 11. METHODS: A case-control study was conducted with asthmatic and non-asthmatic children aged 5 to 11 years in Cuenca-Ecuador. Data on allergic diseases...
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