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Nasal Cell DNA Methylation, Inflammation, Lung Function and Wheezing in Children with Asthma

1 Feb 2012

Abstract excerpt

AIMS: DNA methylation is increasingly proposed as a mechanism for underlying asthma-related inflammation. However, epigenetic studies are constrained by uncertainties on whether samples that can be easily collected in human individuals can provide informative results. METHODS: Two nasal cell DNA samples were collected on different days by nasal brushings from 35 asthmatic children aged between 8 and 11 years old....

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PMID: 22332661
DOI: 10.2217/epi.11.106

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