Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcriptome analysis of non human primate-induced pluripotent stem cell-derived cardiomyocytes in 2D monolayer culture vs. 3D engineered heart tissue.

Cardiovascular research - 27 Jul 2021

Yang Huaxiao, Shao Ningyi, Holmström Alexandra, Zhao Xin, Chour Tony, Chen Haodong, Itzhaki Ilanit, Wu Haodi, Ameen Mohamed, Cunningham Nathan J, Tu Chengyi, Zhao Ming-Tao, Tarantal Alice F, Abilez Oscar J, Wu Joseph C

Abstract excerpt

AIMS: Stem cell therapy has shown promise for treating myocardial infarction via re-muscularization and paracrine signalling in both small and large animals. Non-human primates (NHPs), such as rhesus macaques (Macaca mulatta), are primarily utilized in preclinical trials due to their similarity to humans, both genetically and physiologically. Currently, induced pluripotent stem cell-derived cardiomyocytes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Hypoxia
Share to Heart Rate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Macaca mulatta

Share to Mice, SCID

Share to Myocardial Ischemia

Share to Myocytes, Cardiac

Share to Paracrine Communication

Share to Tissue Engineering

Source

Open in PubMed Open full text

Identifiers

PMID: 33002105
DOI: 10.1093/cvr/cvaa281
PMCID: PMC8318103

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcriptome analysis of non human primate-induced pluripotent stem cell-derived cardiomyocytes in 2D monolayer culture vs. 3D engineered heart tissue.PMID 33002105Read ↗

Comparison of Non-human Primate versus Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Treatment of Myocardial InfarctionSemantic proximity Read ↗

Inter-species differences in response to hypoxia in iPSC-derived cardiomyocytes from humans and chimpanzeesSemantic proximity Read ↗

Multicellular Human Cardiac Organoids Transcriptomically Model Distinct Tissue-Level Features of Adult MyocardiumSemantic proximity Read ↗

Naturally aligned cell delivery platform to augment post-infarction neovasculature and ventricular remodelingSemantic proximity Read ↗

Combining cell and gene therapy to advance cardiac regenerationSemantic proximity Read ↗

Human iPSC-derived Committed Cardiac Progenitors Generate Cardiac Tissue Grafts in a Swine Ischemic Cardiomyopathy Model without Triggering Ventricular ArrhythmiasSemantic proximity Read ↗

Stem Cell Therapy for Myocardial Infarction Recovery: Advances, Challenges, and Future DirectionsSemantic proximity Read ↗

Permanently Hypoxic Cell Culture Yields Rat Bone Marrow Mesenchymal Cells with Higher Therapeutic Potential in the Treatment of Chronic Myocardial Infarction.Semantic proximity Read ↗

Human iPSC-engineered cardiac tissue platform faithfully models important cardiac physiology.Semantic proximity Read ↗

Pre-clinical evaluation of the efficacy and safety of human induced pluripotent stem cell-derived cardiomyocyte patchSemantic proximity Read ↗

Human hearts have an intrinsic regenerative potential following myocardial infarctionSemantic proximity Read ↗

Transplantation of IPSC-Derived Cardiomyocyte Patches for Ischemic CardiomyopathySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.