Article
ColiSeq: a multiplex amplicon assay that provides strain level resolution of Escherichia coli directly from clinical specimens.
Microbiology spectrum - 4 Jun 2024
Williamson Charles H D, Vazquez Adam J, Nunnally Amalee E, Kyger Kristen, Fofanov Viacheslav Y, Furstenau Tara N, Hornstra Heidie M, Terriquez Joel, Keim Paul, Sahl Jason W
Abstract excerpt
Escherichia coli is a diverse pathogen, causing a range of disease in humans, from self-limiting diarrhea to urinary tract infections (UTIs). Uropathogenic E. coli (UPEC) is the most frequently observed uropathogen in UTIs, a common disease in high-income countries, incurring billions of dollars yearly in treatment costs. Although E. coli is easily grown and identified in the clinical laboratory, genotyping the...
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