Article
A parsimonious 3-gene signature predicts clinical outcomes in an acute myeloid leukemia multicohort study
23 Apr 2019
Abstract excerpt
Abstract Acute myeloid leukemia (AML) is a genetically heterogeneous hematological malignancy with variable responses to chemotherapy. Although recurring cytogenetic abnormalities and gene mutations are important predictors of outcome, 50% to 70% of AMLs harbor normal or risk-indeterminate karyotypes. Therefore, identifying more effective biomarkers predictive of treatment success and failure is essential for...
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