Genomic testing identifies monogenic causes in patients with very early-onset inflammatory bowel disease: a multicenter survey in an Iranian cohort.

doi:10.1093/cei/uxae037

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Article

Genomic testing identifies monogenic causes in patients with very early-onset inflammatory bowel disease: a multicenter survey in an Iranian cohort.

Clinical and experimental immunology - 20 Jun 2024

Eslamian Golnaz, Jamee Mahnaz, Momen Tooba, Rohani Pejman, Ebrahimi Sarehossadat, Mesdaghi Mehrnaz, Ghadimi Soodeh, Mansouri Mahboubeh, Mahdaviani Seyed Alireza, Sadeghi-Shabestari Mahnaz, Fallahpour Morteza, Shamsian Bibi Shahin, Eslami Narges, Sharafian Samin, Dara Naghi, Nasri Peiman, Amini Niloufar, Enayat Javad, Fallahi Mazdak, Ghasemi Hashtrodi Leila, Shojaei Mohammad, Guevara Becerra Martha, Uhlig Holm H, Chavoshzadeh Zahra

Abstract excerpt

Patients with very early-onset inflammatory bowel disease (VEO-IBD) may present because of underlying monogenic inborn errors of immunity (IEI). Strong differences have been observed in the causes of monogenic IBD among ethnic populations. This multicenter study was carried out on 16 Iranian patients with VEO-IBD. We reviewed clinical and basic immunologic evaluation including flow cytometry and immunoglobulin...

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PMID: 38651248
DOI: 10.1093/cei/uxae037
PMCID: PMC11188541

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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