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Article

The causality between Type 2 diabetes and breast cancer: a bidirectional two-sample Mendelian randomization study.

Future oncology (London, England) - 1 Jan 2024

Zhang Lihan, Liu Shuochuan, Yue Guangxing, Niu Hong, Hu Mengjin, Zheng Yuling, Tang Jingwen

Abstract excerpt

Objective: Observational studies showed that Type 2 diabetes increased the risk of breast cancer, and vice versa. However, it is uncertain whether the link is causal or just due to confounding factors. Using bidirectional Mendelian randomization analysis, we assessed the bidirectional causal relationship from a genetic level. Methods: Large genome-wide association studies yielded summary-level data for Type 2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38639577
DOI: 10.2217/fon-2023-0708
PMCID: PMC11318721

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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