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Article

Aortic Stenosis and Renal Function: A Bidirectional Mendelian Randomization Analysis.

Journal of the American Heart Association - 7 May 2024

Ciofani Jonathan L, Han Daniel, Allahwala Usaid K, Bhindi Ravinay

Abstract excerpt

BACKGROUND: Large observational studies have demonstrated a clear inverse association between renal function and risk of aortic stenosis (AS). Whether this represents a causal, reverse causal or correlative relationship remains unclear. We investigated this using a bidirectional 2-sample Mendelian randomization approach. METHODS AND RESULTS: We collected summary statistics for the primary analysis of chronic...

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Share to Aortic Valve Stenosis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Renal Insufficiency, Chronic

Source

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Identifiers

PMID: 38639330
DOI: 10.1161/JAHA.123.034102
PMCID: PMC11179900

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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