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Article

The fatal contribution of serine protease-related genetic variants to COVID-19 outcomes

27 Mar 2024

Abstract excerpt

Introduction Serine proteases play a critical role during SARS-CoV-2 infection. Therefore, polymorphisms of transmembrane protease serine 2 (TMPRSS2) and serpine family E member 1 (SERPINE1) could help to elucidate the contribution of variability to COVID-19 outcomes. Methods To evaluate the genetic variants of the genes previously associated with COVID-19 outcomes, we performed a cross-sectional study in which...

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PMID: 38601158
DOI: 10.3389/fimmu.2024.1335963

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