Article
Poor visual prognosis of Asian patients with 3460 mitochondrial DNA mutation in Leber's hereditary optic neuropathy.
Canadian journal of ophthalmology. Journal canadien d'ophtalmologie - 1 Dec 2024
Yang Hee Kyung, Seong Moon-Woo, Kim Ji Yeon, Park Sung Sup, Hwang Jeong-Min
Abstract excerpt
BACKGROUND: Among the 3 primary mutations of Leber's hereditary optic neuropathy (LHON), the incidence of LHON with a mutation at nucleotide position 3460 is the lowest in Asians. Therefore, information about the clinical manifestations of LHON mutations in Asians with the 3460 mutation is limited. OBJECTIVE: To determine the clinical manifestations including visual prognosis of Asians with the LHON 3460...
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