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Article

mtDNA m.3635G>A may be classified as a common primary mutation for Leber hereditary optic neuropathy in the Chinese population.

Biochemical and biophysical research communications - 10 Dec 2010

Jia Xiaoyun, Li Shiqiang, Wang Panfeng, Guo Xiangming, Zhang Qingjiong

Abstract excerpt

Leber hereditary optic neuropathy (LHON) is the most common cause of sudden blindness in young adults and is caused by mtDNA mutations. At least 30 mutations have been identified but only the three common mutations (m.3460G>A, m.11778G>A, and m.14484T>C) have been extensively studied. Most other...

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Identifiers

PMID: 21074518
DOI: 10.1016/j.bbrc.2010.11.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21074518-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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