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Construction and experimental validation of a novel ferroptosis‐related gene signature for myelodysplastic syndromes

1 Apr 2024

Abstract excerpt

BACKGROUND: Myelodysplastic syndromes (MDS) are clonal hematopoietic disorders characterized by morphological abnormalities and peripheral blood cytopenias, carrying a risk of progression to acute myeloid leukemia. Although ferroptosis is a promising target for MDS treatment, the specific roles of ferroptosis-related genes (FRGs) in MDS diagnosis have not been elucidated. METHODS: MDS-related microarray data were...

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PMID: 38578040
DOI: 10.1002/iid3.1221

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