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Integrated assessment of the clinical and biological value of ferroptosis-related genes in multiple myeloma

23 Oct 2022

Abstract excerpt

BACKGROUND: Ferroptosis is an iron-dependent mode of cell death that could be induced by erastin and exert antitumor effects. However, the clinical and biological roles of ferroptosis-related gene (FRG) signature and the therapeutic value of erastin in multiple myeloma (MM) remained unknown. METHODS: Clinical and gene expression data of MM subjects were extracted from the Gene Expression Omnibus (GEO) public...

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PMID: 36274128
DOI: 10.1186/s12935-022-02742-4

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