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Article

Molecular Evaluation of Low-grade Low-stage Endometrial Cancer With and Without Recurrence.

International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 May 2022

Matrai Cathleen E, Ohara Kentaro, Eng Kenneth Wha, Glynn Shannon M, Chandra Pooja, Chatterjee-Paer Sudeshna, Motanagh Samaneh, Mirabelli Susanna, Kurtis Boaz, He Bing, Sigaras Alexandros, Gupta Divya, Chapman-Davis Eloise, Holcomb Kevin, Sboner Andrea, Elemento Olivier, Ellenson Lora Hedrick, Mosquera Juan Miguel

Abstract excerpt

Low-grade, low-stage endometrioid carcinomas (LGLS EC) demonstrate 5-yr survival rates up to 95%. However, a small subset of these tumors recur, and little is known about prognostic markers or established mutation profiles associated with recurrence. The goal of the current study was to identify the molecular profiles of the primary carcinomas and the genomic differences between primary tumors and subsequent...

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Identifiers

PMID: 34483300
DOI: 10.1097/PGP.0000000000000798
PMCID: PMC9018213

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