Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The CRISPR-Cas9 induced CCR5 Δ32 mutation as a potent gene therapy methodology for resistance to HIV-1 variant: a review.

European review for medical and pharmacological sciences - 1 Mar 2024

Saifullah M, Laghzaoui O, Ozyahyalar H, Irfan A

Abstract excerpt

Human Immunodeficiency Virus (HIV) has continuously been the greatest epidemic for humanity over a period spanning almost five decades. With no specific cure or treatment available to date despite extensive research, the C-C Chemokine Receptor 5, Delta 32 (CCR5 Δ32) allele genetic point mutation plays an imperative role in the prevention of acquired immunodeficiency syndrome (AIDS). This comprehensive study aims...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acquired Immunodeficiency Syndrome
Share to CRISPR-Cas Systems

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Genetic Therapy

Share to HIV Infections

Share to Polymorphism, Single Nucleotide

Share to Receptors, CCR5

Source

Identifiers

PMID: 38567606
DOI: 10.26355/eurrev_202403_35751

Genes

CCR5
CD4
CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The CRISPR-Cas9 induced CCR5 Δ32 mutation as a potent gene therapy methodology for resistance to HIV-1 variant: a review.PMID 38567606Read ↗

CCR5-Δ32 biology, gene editing, and warnings for the future of CRISPR-Cas9 as a human and humane gene editing toolSemantic proximity Read ↗

Legacy of a magic gene-CCR5-∆32: From discovery to clinical benefit in a generation.Semantic proximity Read ↗

HEK293T Cells Are Heterozygous for CCR5 Delta 32 Mutation.Semantic proximity Read ↗

Biallelic, Selectable, Knock-in Targeting of CCR5 via CRISPR-Cas9 Mediated Homology Directed Repair Inhibits HIV-1 Replication.Semantic proximity Read ↗

CRISPR Cas13a: A Potential Therapeutic Cure for HIV Infection in HumansSemantic proximity Read ↗

Treatment strategies for HIV infection with emphasis on role of CRISPR/Cas9 gene: Success so far and road aheadSemantic proximity Read ↗

PlmCas12e (CasX2) cleavage of CCR5: impact of guide RNA spacer length and PAM sequence on cleavage activity.Semantic proximity Read ↗

HIV and the CCR5-Delta32 resistance allele.Semantic proximity Read ↗

Current application of CRISPR/Cas9 gene-editing technique to eradication of HIV/AIDSSemantic proximity Read ↗

CRISPR/Cas9-Mediated CCR5 Ablation in Human Hematopoietic Stem/Progenitor Cells Confers HIV-1 Resistance In Vivo.Semantic proximity Read ↗

The Influence Between C-C Chemokine Receptor 5 Genetic Polymorphisms and the Type-1 Human Immunodeficiency Virus: A 20-Year Review.Semantic proximity Read ↗

Beyond HIV infection: Neglected and varied impacts of CCR5 and CCR5Δ32 on viral diseases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.