Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Expansion of the genotypic and phenotypic spectrum and treatment of four children with Steroid-resistant nephrotic syndrome due to variants of TRPC6 gene].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 10 Apr 2024

Zhao Gongping, Li Jitong, Liu Yujie, Li Guangbo, Zhang Yanmin, Zhang Shufeng, Liu Cuihua

Abstract excerpt

OBJECTIVE: To summarize the clinical and genetic characteristics, treatment and prognosis of four children with Steroid-resistant nephrotic syndrome (SRNS) due to variants of TRPC6 gene. METHODS: Clinical data of four children with SRNS admitted to Children's Hospital Affiliated to Zhengzhou University between May 2020 and August 2022 were collected. Peripheral blood samples were collected from the children and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child
Share to Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glomerulosclerosis, Focal Segmental

Share to Kidney

Share to Mutation

Share to Nephrotic Syndrome

Share to Phenotype

Share to TRPC6 Cation Channel

Source

Identifiers

PMID: 38565515
DOI: 10.3760/cma.j.cn511374-20230309-00120

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Expansion of the genotypic and phenotypic spectrum and treatment of four children with Steroid-resistant nephrotic syndrome due to variants of TRPC6 gene].PMID 38565515Read ↗

Heterozygous missense variant in TRPC6 in a boy with rapidly progressive infantile nephrotic syndrome associated with diffuse mesangial sclerosis.Semantic proximity Read ↗

TRPC6 gene variants in Turkish children with steroid-resistant nephrotic syndrome.Semantic proximity Read ↗

[TRPC6 mutations in children with steroid-resistant nephrotic syndrome].Semantic proximity Read ↗

TRPC6 mutations in children with steroid-resistant nephrotic syndrome and atypical phenotype.Semantic proximity Read ↗

254C>G: a TRPC6 promoter variation associated with enhanced transcription and steroid-resistant nephrotic syndrome in Chinese children.Semantic proximity Read ↗

Monogenic Causes Identified in 23.68% of Children with Steroid-Resistant Nephrotic Syndrome: A Single-Centre StudySemantic proximity Read ↗

Mutation spectrum of genes associated with steroid-resistant nephrotic syndrome in Chinese children.Semantic proximity Read ↗

Mutational landscape of TRPC6, WT1, LMX1B, APOL1, PTPRO, PMM2, LAMB2 and WT1 genes associated with Steroid resistant nephrotic syndrome.Semantic proximity Read ↗

In silico analysis of functional nsSNPs in human TRPC6 gene associated with steroid resistant nephrotic syndrome.Semantic proximity Read ↗

Genetic analysis of Indian patients with steroid-resistant nephrotic syndrome in childrenSemantic proximity Read ↗

Causal and putative pathogenic mutations identified in 39% of children with primary steroid-resistant nephrotic syndrome in South Africa.Semantic proximity Read ↗

Genetic tests in children with steroid-resistant nephrotic syndromeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.