Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TRPC6 gene variants in Turkish children with steroid-resistant nephrotic syndrome.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Jan 2012

Mir Sevgi, Yavascan Onder, Berdeli Afig, Sozeri Betul

Abstract excerpt

BACKGROUND: In steroid-resistant nephrotic syndrome (SRNS), a considerable number of patient progress to end-stage renal disease (ESRD), despite aggressive therapy. The latest advance in familial focal segmental glomerulosclerosis (FSGS) has been the discovery of a mutant form of canonical transient receptor potential channel 6 (TRPC6) leading to FSGS through unclear mechanisms. The aim of this study is to screen...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Anti-Inflammatory Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance

Share to Nephrotic Syndrome

Share to Prednisolone

Share to TRPC Cation Channels

Share to TRPC6 Cation Channel

Share to Turkey

Source

Identifiers

PMID: 21511817
DOI: 10.1093/ndt/gfr202

Genes

TRPC6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TRPC6 gene variants in Turkish children with steroid-resistant nephrotic syndrome.PMID 21511817Read ↗

TRPC6 mutations in children with steroid-resistant nephrotic syndrome and atypical phenotype.Semantic proximity Read ↗

254C>G: a TRPC6 promoter variation associated with enhanced transcription and steroid-resistant nephrotic syndrome in Chinese children.Semantic proximity Read ↗

[Expansion of the genotypic and phenotypic spectrum and treatment of four children with Steroid-resistant nephrotic syndrome due to variants of TRPC6 gene].Semantic proximity Read ↗

In silico analysis of functional nsSNPs in human TRPC6 gene associated with steroid resistant nephrotic syndrome.Semantic proximity Read ↗

Heterozygous missense variant in TRPC6 in a boy with rapidly progressive infantile nephrotic syndrome associated with diffuse mesangial sclerosis.Semantic proximity Read ↗

Unexpected role of TRPC6 channel in familial nephrotic syndrome: does it have clinical implications?Semantic proximity Read ↗

Natural history of patients with familial focal segmental glomerulosclerosis associated with TRPC6 variants.Semantic proximity Read ↗

Screening of ACTN4 and TRPC6 mutations in a Chinese cohort of patients with adult-onset familial focal segmental glomerulosclerosis.Semantic proximity Read ↗

TRPC6 and FSGS: the latest TRP channelopathy.Semantic proximity Read ↗

[TRPC6 mutations in children with steroid-resistant nephrotic syndrome].Semantic proximity Read ↗

TRPC Channels in Proteinuric Kidney DiseasesSemantic proximity Read ↗

TRPC6 gene variants in Czech adult patients with focal segmental glomerulosclerosis and minimal change disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.