Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MucoRice-CTB line 19A, a new marker-free transgenic rice-based cholera vaccine produced in an LED-based hydroponic system

15 Mar 2024

Abstract excerpt

We previously established the selection-marker-free rice-based oral cholera vaccine (MucoRice-CTB) line 51A for human use by Agrobacterium -mediated co-transformation and conducted a double-blind, randomized, placebo-controlled phase I trial in Japan and the United States. Although MucoRice-CTB 51A was acceptably safe and well tolerated by healthy Japanese and U.S. subjects and induced CTB-specific antibodies...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CRISPR and Genetic Engineering
Share to Transgenic Plants and Applications
Share to Viral gastroenteritis research and epidemiology

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38559768
DOI: 10.3389/fpls.2024.1342662

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MucoRice-CTB line 19A, a new marker-free transgenic rice-based cholera vaccine produced in an LED-based hydroponic systemPMID 38559768Read ↗

Induction of toxin-specific neutralizing immunity by molecularly uniform rice-based oral cholera toxin B subunit vaccine without plant-associated sugar modification.Semantic proximity Read ↗

Development of Antibody-Fragment–Producing Rice for Neutralization of Human NorovirusSemantic proximity Read ↗

Detection of Potential Phytochemicals against ctxAB Toxin to Combat CholeraSemantic proximity Read ↗

Development of transgenic algae strain expressing CTB-M2e fusion gene an approach towards the development of a universal edible vaccine in algaeSemantic proximity Read ↗

Mutants in the ADP-ribosyltransferase cleft of cholera toxin lack diarrheagenicity but retain adjuvanticity.Semantic proximity Read ↗

Genetic stability, environmental safety and field adaptation assessment of transgenic rice with chicken Newcastle disease HN proteinSemantic proximity Read ↗

Broad specificity immunoassay for detection of Bacillus thuringiensis Cry toxins through engineering of a single chain variable fragment with mutagenesis and screening.Semantic proximity Read ↗

High-throughput detection of genetically modified rice ingredients in foods using multiplex polymerase chain reaction coupled with high-performance liquid chromatography methodSemantic proximity Read ↗

A novel approach to generate a recombinant toxoid vaccine against Clostridium difficile.Semantic proximity Read ↗

Harnessing Plant Chloroplasts for Oral Delivery of a Multi-epitope HPV Vaccine: Toward Cost-Effective Systemic and Mucosal ImmunizationSemantic proximity Read ↗

Genetic Stability and Molecular-Based Environmental Safety Assessment of Transgenic Rice Harboring the HN Gene of Chicken Newcastle Disease VirusSemantic proximity Read ↗

Construction and preclinical evaluation of mmCT, a novel mutant cholera toxin adjuvant that can be efficiently produced in genetically manipulated Vibrio cholerae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.