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Article

Clinical Implementation of a Noninvasive, Multi-Analyte Droplet Digital PCR Test to Screen for Androgen Receptor Alterations.

The Journal of molecular diagnostics : JMD - 1 Jun 2024

Stitz Regina, Stoiber Franz, Silye Renè, Vlachos Georgios, Andaloro Silvia, Rebhan Elisabeth, Dunzinger Michael, Pühringer Franz, Gallo Caroline, El-Heliebi Amin, Heitzer Ellen, Hauser-Kronberger Cornelia

Abstract excerpt

Alterations of the androgen receptor (AR) are associated with resistance to AR-directed therapy in prostate cancer. Thus, it is crucial to develop robust detection methods for AR alterations as predictive biomarkers to enable applicability in clinical practice. We designed and validated five multiplex droplet digital PCR assays for reliable detection of 12 AR targets including AR amplification, AR splice variant...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38522838
DOI: 10.1016/j.jmoldx.2024.02.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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