Article
Metabolomics identifies phenotypic biomarkers of amino acid metabolism in milk allergy and sensitized tolerance.
The Journal of allergy and clinical immunology - 1 Jul 2024
Zhang Qiaozhi, Wang Hui, Zhang Shenyu, Chen Mingwu, Gao Zhongshan, Sun Jinlyu, Wang Jizhou, Fu Linglin
Abstract excerpt
BACKGROUND: A substantial proportion of sensitized individuals tolerate suspected foods without developing allergic symptoms; this phenomenon is known as sensitized tolerance. The immunogenic and metabolic features underlying the sensitized-tolerant phenotype remain largely unknown. OBJECTIVE: We aimed to uncover the metabolic signatures associated with clinical milk allergy (MA) and sensitized tolerance using...
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