Article
Risk factors for glioblastoma are shared by other brain tumor types.
Human & experimental toxicology - 1 Jan 2000
Smith Carr J, Perfetti Thomas A, Chokshi Chirayu, Venugopal Chitra, Ashford J Wesson, Singh Sheila K
Abstract excerpt
The reported risk factors for glioblastoma (GBM), i.e., ionizing radiation, Li-Fraumeni syndrome, Neurofibromatosis I, and Turcot syndrome, also increase the risk of other brain tumor types. Risk factors for human GBM are associated with different oncogenic mutation profiles. Pedigreed domestic dogs with a shorter nose and flatter face (brachycephalic dogs) display relatively high rates of glioma formation. The...
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