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Article

Identification of 14 novel susceptibility loci for diaphragmatic hernia development and their biological and clinical implications: results from the UK Biobank.

Surgical endoscopy - 1 Oct 2022

Campbell Michelle, Wei Jun, Attaar Mikhail, Wu Hoover, Wong Harry J, Ujiki Michael B, Xu Jianfeng

Abstract excerpt

INTRODUCTION: Genetic contributions to hernia development are incompletely understood. This study performed the first comprehensive genome-wide association study (GWAS) for diaphragmatic hernia using a large population-based cohort in the UK Biobank (UKB). METHODS AND PROCEDURES: Two-stage GWAS (discovery and confirmation) was performed for diaphragmatic hernia in the UKB. Briefly, 275,549 and 91,850 subjects...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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PMID: 36076102
DOI: 10.1007/s00464-022-09064-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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