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Hepatitis E virus infects human testicular tissue and Sertoli cells.

Emerging microbes & infections - 1 Dec 2024

Liu Tianxu, Cao Yalei, Weng Jiaming, Gao Songzhan, Jin Zirun, Zhang Yun, Yang Yuzhuo, Zhang He, Xia Changyou, Yin Xin, Luo Yong, He Qiyu, Jiang Hui, Wang Lin, Zhang Zhe

Abstract excerpt

Globally, hepatitis E virus (HEV) infections are prevalent. The finding of high viral loads and persistent viral shedding in ejaculate suggests that HEV replicates within the human male genital tract, but its target organ is unknown and appropriate models are lacking. We aimed to determine the HEV tropism in the human testis and its potential influence on male reproductive health. We conducted an ex vivo culture...

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Hepatitis E
Hepatitis E virus
Rabbits
Sertoli Cells
Tacrolimus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Virus Replication

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PMID: 38517709
DOI: 10.1080/22221751.2024.2332657
PMCID: PMC11057402

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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