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SARS-CoV-2 replicates in the human testis with slow kinetics and has no major deleterious effects ex vivo

13 Oct 2023

Abstract excerpt

ABSTRACT SARS-CoV-2, the etiological agent of the ongoing Covid-19 pandemic, is a respiratory virus that infects several organs beyond the lungs. The alterations of semen parameters, testicular morphology, and testosteronemia reported in Covid-19 patients, along with the high expression of SARS-CoV-2 main receptor ACE2 in the testis, raise questions about the underlying mechanisms. Using a previously validated ex...

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PMID: 37830818
DOI: 10.1128/jvi.01104-23

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