Article
Skin Cancer Risk Is Increased by Somatic Mutations Detected Noninvasively in Healthy-Appearing Sun-Exposed Skin.
The Journal of investigative dermatology - 1 Oct 2024
Kaur Kulvinder, Ai Rizi, Perry Allyson G, Riley Bae, Roberts Emma L, Montano Erica N, Han Jessica, Roacho Joanna, Lopez Brenda Garcia, Skelsey Maral K, Childs Maria V, Childs James N, Dobak John, Ibarra Claudia, Jansen Burkhard, Clarke Loren E, Stone Steven, Whitaker John W
Abstract excerpt
Skin cancer risk is increased by exposure to ultraviolet radiation (UVR). Because UVR exposure accumulates over time and lighter skin is more susceptible to UVR, age and skin tone are risk factors for skin cancer. However, measurements of somatic mutations in healthy-appearing skin have not been used to calculate skin cancer risk. In this study, we developed a noninvasive test that quantifies somatic mutations in...
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