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Immune-related genes with APA in microenvironment indicate risk stratification and clinical prognosis in grade II/III gliomas

5 Feb 2021

Abstract excerpt

Tumor microenvironment and alternative polyadenylation (APA) have drawn more attention in cancer research. However, their roles in grade II and III gliomas, termed as lower-grade glioma (LGG) in this study, remain to be fully elucidated. Here, we conducted this study and found that stromal and immune scores were elevated in higher grade and isocitrate dehydrogenase (IDH) wild-type glioma. Besides, higher stromal...

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Cancer-related molecular mechanisms research
Ferroptosis and cancer prognosis
Glioma Diagnosis and Treatment

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33665000
DOI: 10.1016/j.omtn.2021.01.033

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