Article
Mechanistic study of the transmission pattern of the SARS-CoV-2 omicron variant.
Proteins - 1 Jun 2024
An Ke, Yang Xianzhi, Luo Mengqi, Yan Junfang, Xu Peiyi, Zhang Honghui, Li Yuqing, Wu Song, Warshel Arieh, Bai Chen
Abstract excerpt
The omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) characterized by 30 mutations in its spike protein, has rapidly spread worldwide since November 2021, significantly exacerbating the ongoing COVID-19 pandemic. In order to investigate the relationship between these mutations and the variant's high transmissibility, we conducted a systematic analysis of the mutational effect on...
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