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Article

BRU1, a novel link between responses to DNA damage and epigenetic gene silencing in Arabidopsis.

Genes & development - 1 Apr 2004

Takeda Shin, Tadele Zerihun, Hofmann Ingo, Probst Aline V, Angelis Karel J, Kaya Hidetaka, Araki Takashi, Mengiste Tesfaye, Mittelsten Scheid Ortrun, Shibahara Kei-ichi, Scheel Dierk, Paszkowski Jerzy

Abstract excerpt

DNA repair associated with DNA replication is important for the conservation of genomic sequence information, whereas reconstitution of chromatin after replication sustains epigenetic information. We have isolated and characterized mutations in the BRU1 gene of Arabidopsis that suggest a novel link between these underlying maintenance mechanisms. Bru1 plants are highly sensitive to genotoxic stress and show...

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Source

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Identifiers

PMID: 15082530
DOI: 10.1101/gad.295404
PMCID: PMC387418

Genes

MRE11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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