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Article

The absence of functional CAF-1 results in deficiencies in H3.3 levels at transcribed loci in Arabidopsis.

Plant physiology - 1 Sept 2026

Yang Fan, Su Yingpei, Xi Weijie, Wang Yafei, Ausin Israel

Abstract excerpt

Eukaryotic organisms organize their genetic material in chromatin rather than naked DNA. Efficient chromatin assembly is essential for all DNA-templated processes, including replication, transcription, and DNA repair. Our research focused on two major histone H3 deposition complexes: Chromatin Assembly Factor (CAF-1) and Histone Regulator A (HIRA). CAF-1 deposits canonical H3 on naked DNA immediately after...

Read the complete abstract on PubMed

Topics

Arabidopsis
Arabidopsis Proteins
Histones
Transcription, Genetic
Chromatin Assembly Factor-1
Chromatin
Gene Expression Regulation, Plant

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Genetic Loci

Transcription Factors

Mutation

Cell Cycle Proteins

Source

Identifiers

PMID: 42680158
DOI: 10.1093/plphys/kiag648

Genes

HIRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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The absence of functional CAF-1 results in deficiencies in H3.3 levels at transcribed loci in Arabidopsis.PMID 42680158Read ↗

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Genome-wide identification, evolutionary, and expression analyses of histone H3 variants in plants.Semantic proximity Read ↗

New functions for an old variant: no substitute for histone H3.3.Semantic proximity Read ↗

Arabidopsis Chromatin Assembly Factor 1 is required for occupancy and position of a subset of nucleosomes.Semantic proximity Read ↗

The double face of the histone variant H3.3.Semantic proximity Read ↗

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Arabidopsis ATRX Modulates H3.3 Occupancy and Fine-Tunes Gene Expression.Semantic proximity Read ↗

The Histone Chaperone HIRA Is a Positive Regulator of Seed Germination.Semantic proximity Read ↗

CAF-1 in Replication and Repair: A Critical Genetic Mediator of Synthesis-Coupled Nucleosome AssemblySemantic proximity Read ↗

NAP1-RELATED PROTEIN1 and 2 negatively regulate H2A.Z abundance in chromatin in Arabidopsis.Semantic proximity Read ↗

Structure of the human HIRA histone chaperone with a nucleosome suggests a stepwise nucleosome assembly mechanismSemantic proximity Read ↗

Histone variants and chromatin assembly in plant abiotic stress responses.Semantic proximity Read ↗

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