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Apolipoprotein E E3/E4 genotype is associated with an increased risk of type 2 diabetes mellitus complicated with coronary artery disease.

BMC cardiovascular disorders - 15 Mar 2024

Chen Wenhao, Li Bin, Wang Hao, Wei Guoliang, Chen Kehui, Wang Weihong, Wang Shen, Liu Yuanliang

Abstract excerpt

OBJECTIVE: Dyslipidemia is a co-existing problem in patients with diabetes mellitus (DM) and coronary artery disease (CAD), and apolipoprotein E (APOE) plays an important role in lipid metabolism. However, the relationship between the APOE gene polymorphisms and the risk of developing CAD in type 2 DM (T2DM) patients remains controversial. The aim of this study was to assess this relationship and provide a...

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Identifiers

PMID: 38491412
DOI: 10.1186/s12872-024-03831-0
PMCID: PMC10941446

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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