Article
Dissecting the Association of Apolipoprotein E Gene Polymorphisms With Type 2 Diabetes Mellitus and Coronary Artery Disease.
Frontiers in endocrinology - 1 Jan 2022
Wu Lei, Zhang Yan, Zhao Hong, Rong Guodong, Huang Peijun, Wang Fang, Xu Ting
Abstract excerpt
Background: Apolipoprotein E (APOE) gene mediates lipoprotein clearance and is one of the most studied candidate genes for type 2 diabetes mellitus (T2DM) and coronary artery disease (CAD). This study was performed to determine the association between APOE polymorphisms and T2DM with and without CAD, and its effect on plasma lipid levels in a Chinese population. Methods: A total of 1,414 subjects involving 869...
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