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Article

Apolipoprotein E E3/E4 genotype is associated with an increased risk of premature coronary artery disease.

BMC cardiovascular disorders - 10 Jul 2024

Li Youqian, Zhong Wei, Huang Changjing, Peng Junyin, Li Hanlin

Abstract excerpt

OBJECTIVE: Dyslipidemia is one of the causes of coronary heart disease (CAD), and apolipoprotein E (APOE) gene polymorphism affects lipid levels. However, the relationship between APOE gene polymorphisms and premature CAD (PCAD, male CAD patients with ≤ 55 years old and female with ≤ 65 years old) risk had different results in different studies. The aim of this study was to assess this relationship and to further...

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Identifiers

PMID: 38987708
DOI: 10.1186/s12872-024-04021-8
PMCID: PMC11234594

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