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Pituitary tumours without distinct lineage differentiation express stem cell marker SOX2

14 Mar 2024

Abstract excerpt

CONTEXT: The recent WHO 2022 Classification of pituitary tumours identified a novel group of 'plurihormonal tumours without distinct lineage differentiation (WDLD)'. By definition, these express multiple combinations of lineage commitment transcription factors, in a monomorphous population of cells. OBJECTIVES: To determine the expression of stem cell markers (SOX2, Nestin, CD133) within tumours WDLD, immature...

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PMID: 38483762
DOI: 10.1007/s11102-024-01385-0

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