Article
Isolation and characterization of progenitor mesenchymal cells in human pituitary tumors.
Cancer gene therapy - 1 Jan 2015
Orciani M, Davis S, Appolloni G, Lazzarini R, Mattioli-Belmonte M, Ricciuti R A, Boscaro M, Di Primio R, Arnaldi G
Abstract excerpt
The Cancer Stem Cells (CSCs) theory suggests that genetic alterations in stem cells are the direct cause for cancer. The evidence for a CSC population that results in pituitary tumors is poor. Some studies report the isolation of CSCs, but a deep characterization of the stemness of these cells is lacking. Here, we report the isolation and detailed characterization of progenitor mesenchymal cells (PMCs) from both...
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