Article
miRNA expression profiling of lung adenocarcinomas: correlation with mutational status.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Dec 2010
Dacic Sanja, Kelly Lindsey, Shuai Yongli, Nikiforova Marina N
Abstract excerpt
MicroRNA (miRNA) expression is deregulated in lung cancer, and some miRNAs are associated with poor prognosis and survival. In this study, we investigated the miRNA expression in lung adenocarcinomas with different oncogenic mutations, including EGFR-positive, KRAS-positive and EGFR/KRAS-negative tumors. The expression of 319 miRNAs was evaluated by Exiqon/Luminex microarray, and expression of individual miRNAs...
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