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Strengthening Bordetella pertussis genomic surveillance by direct sequencing of residual positive specimens

6 Mar 2024

Abstract excerpt

ABSTRACT Whole-genome sequencing (WGS) of microbial pathogens recovered from patients with infectious disease facilitates high-resolution strain characterization and molecular epidemiology. However, increasing reliance on culture-independent methods to diagnose infectious diseases has resulted in few isolates available for WGS. Here, we report a novel culture-independent approach to genome characterization of...

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PMID: 38445858
DOI: 10.1128/jcm.01653-23

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