Article
Evaluation of the drug-drug interaction between triazole antifungals and cystic fibrosis transmembrane conductance regulator modulators in a real-life cohort.
Medical mycology - 7 Mar 2024
Jansen Anouk M E, Eggermont Margot N, Wilms Erik B, Aziz Sami, Reijers Monique, Roukema Jolt, Warris Adilia, Brüggemann Roger J M, van der Meer Renske
Abstract excerpt
Limited data on the clinical management of drug-drug interactions between triazoles and Cystic Fibrosis transmembrane conductance regulator (CFTR) modulators are available. We retrospectively evaluated azole target attainment and dose adaptations in patients from two Dutch CF centres concomitantly receiving triazoles and CFTR modulators. In total, 21 patients with 59 triazole trough concentrations were evaluated....
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