Estimates of heterozygosity from single nucleotide polymorphism markers are context-dependent and often wrong.

Abstract excerpt

Genetic diversity is frequently described using heterozygosity, particularly in a conservation context. Often, it is estimated using single nucleotide polymorphisms (SNPs); however, it has been shown that heterozygosity values calculated from SNPs can be biased by both study design and filtering parameters. Though solutions have been proposed to address these issues, our own work has found them to be inadequate...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Alleles
• Share to Genetics, Population
• Share to Heterozygote