Article
To what extent do microsatellite markers reflect genome-wide genetic diversity in natural populations?
Molecular ecology - 1 Sept 2008
Väli Ulo, Einarsson Annika, Waits Lisette, Ellegren Hans
Abstract excerpt
Microsatellite variability is widely used to infer levels of genetic diversity in natural populations. However, the ascertainment bias caused by typically selecting only the most polymorphic markers in the genome may lead to reduced sensitivity for judging genome-wide levels of genetic diversity. To test this potential limitation of microsatellite-based approaches, we assessed the degree of nucleotide diversity...
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