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Former smoking associated with epigenetic modifications in human granulosa cells among women undergoing assisted reproduction

29 Feb 2024

Abstract excerpt

Smoking exposure during adulthood can disrupt oocyte development in women, contributing to infertility and possibly adverse birth outcomes. Some of these effects may be reflected in epigenome profiles in granulosa cells (GCs) in human follicular fluid. We compared the epigenetic modifications throughout the genome in GCs from women who were former (N = 15) versus never smokers (N = 44) undergoing assisted...

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PMID: 38424222
DOI: 10.1038/s41598-024-54957-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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