Article
Genetic mutation patterns among glioblastoma patients in the Taiwanese population - insights from a single institution retrospective study.
Cancer gene therapy - 1 Jun 2024
Huang Yu-Fen, Chiao Ming-Tsang, Hsiao Tzu-Hung, Zhan Yong-Xiang, Chen Tse-Yu, Lee Chung-Hsin, Liu Szu-Yuan, Liao Chih-Hsiang, Cheng Wen-Yu, Yen Chun-Ming, Lai Chih-Ming, Chen Jun-Peng, Shen Chiung-Chyi, Yang Meng-Yin
Abstract excerpt
This study utilized Next-Generation Sequencing (NGS) to explore genetic determinants of survival duration in Glioblastoma Multiforme (GBM) patients. We categorized 30 primary GBM patients into two groups based on their survival periods: extended survival (over two years, N = 17) and abbreviated survival (under two years, N = 13). For identifying pathogenic or likely pathogenic variants, we leveraged the ClinVar...
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